Growing Strong Industries
Developing New Ideas
Nurturing Natural Resources
Developing New Ideas
Nurturing Natural Resources
Oksana M. Kolomitsyna
Research Fellow
Phone. 218-720-2727
Fax. 218-720-4329
E-mail: okolomit@nrri.umn.edu
Education
M.S. in Chemistry, with a major in Organic Chemistry from National Technical University of Ukraine (Kiev Polytechnic Institute), Department of Chemistry and Chemical Technology (1989-1995).
Employment
2003- present, Research Fellow, Natural Resources Research Institute, University of Minnesota Duluth
1997- 2003, Research Specialist, Natural Resources Research Institute, University of Minnesota Duluth
1995-1997, Chemist Engineer, Station of Water Purification and Preparation, Ukraine
Research Interests
- Synthetic organic chemistry.
- Chemistry of natural products (terpenes and fatty acids). The development of new routes of natural products
- Production from natural sources for the purpose of using them as starting materials for organic syntheses.
- Process development of natural products production.
- Chemical modification of natural products for biological tests.
- Synthesis of drugs and drug intermediates base on a triterpenes.
Patents
- Krasutsky, Pavel A.; Kolomitsyna, Oksana. Methods of Manufacturing Bioactive 3-Esters of Betulinic Aldehyde and Betulinic Acid. United States Patent Application 20090023698, January 22, 2009.
- Krasutsky, Pavel A.; Avilov, Dmytro; Sergeeva, Tatiana; Krasutskyy, Dmytro A.; Kolomitsyna, Oksana. Triterpene Quaternary Salts as Biologicaly Active Surfactants. United States Patent 7,410,958, August 12, 2008.
- Krasutsky, Pavel A.; Avilov, Dmytro; Sergeeva, Tatiana; Krasutskyy, Dmytre A.; Kolomitsyna, Oksana. Triterpene Quaternary Salts as Biologicaly Active Surfactants. United States Patent Application 20070259842, November 8, 2007.
- Krasutsky, Pavel A.; Avilov, Dmytro; Sergeeva, Tatiana; Krasutskyy, Dmytre A.; Kolomitsyna, Oksana. Triterpene Quaternary Salts as Biologicaly Active Surfactants. United States Patent Application 20070259839, November 8, 2007.
- Krasutsky, Pavel A.; Avilov, Dmytro; Sergeeva, Tatiana; Krasutskyy, Dmytre A.; Kolomitsyna, Oksana. Triterpene Quaternary Salts as Biologicaly Active Surfactants. United States Patent Application 20070244081, October 18, 2007.
- Krasutsky, Pavel A.; Kolomitsyn, Igor V.; Holy, Jon M.; Perkins, Edward Leon; Kolomitsyna, Oksana. Therapeutic Triterpenoids. International Patent Application WO/2007/121352, October 25, 2007.
- Krasutsky, Pavel A.; Avilov, Dmytro; Sergeeva, Tatiana; Krasutskyy, Dmytro A.; Kolomitsyna, Oksana. Triterpene Quaternary Salts as Biologicaly Active Surfactants. United States Patent 7,199,114, April 3, 2007.
- Krasutsky, Pavel A.; Kolomitsyna, Oksana. Methods of Manufacturing Bioactive 3-Esters of Betulinic Aldehyde and Betulinic Acid. International Patent Application WO/2006/105356, October 5, 2006.
- Krasutsky, Pavel, A.; Kolomitsyna, Oksana; Krasutskyy, Dmytro, A.; Kacharov, Oleksiy, D.; Kolomitsyn, Igor, V. Method for Obtaining Natural Products from Plant Material. International Patent Application WO/2005/047304, May 26, 2005.
- Krasutsky, Pavel A.; Avilov, Dmytro; Sergeeva, Tatiana; Krasutskyy, Dmytro A.; Kolomitsyna, Oksana. Triterpene Quaternary Salts as Biologicaly Active Surfactants. United States Patent Application 20050059642, March 17, 2005.
- Krasutsky, Pavel A.; Avilov, Dmytro; Sergeeva, Tatiana; Krasutskyy, Dmytro A.; Kolomitsyna, Oksana. Triterpene Quaternary Salts as Biologicaly Active Surfactants. International Patent Application WO/2003/062260, July 31, 2003.
Published Articles
- Casey R. Dorr, Sergiy Yemets, Oksana Kolomitsyna, Pavel Krasutsky and Louis M. Mansky “Triterpene derivatives that inhibit human immunodeficiency virus type 1 replication” Bioorganic & Medicinal Chemistry Letters, Volume 21, Issue 1, 1 January 2011, Pages 542-545
- Holy J, Kolomitsyna O, Krasutsky D, Oliveira PJ, Perkins E, Krasutsky PA. “Dimethylaminopyridine derivatives of lupane triterpenoids are potent disruptors of mitochondrial structure and function” Bioorganic & Medicinal Chemistry, Volume 18, Issue 16, 15 August 2010, Pages 6080-6088
Presentations
- 2006, “Triterpenes and Their Derivatives against Bacillus anthracis and Staphylococcus aureus” with co-authors D.Missiakas and O.Schneewind (from University of Chicago, Department of Microbiology), D.Krasutskyy, P.Krasutsky at the GLRCE 4th Annual Meeting on December 1 in Hilton Head Island, SC. Award for the best presentation.
- 1995 Diploma Dissertation: "The project of industrial manufacture of medication "Diphenine" with the planned capacity 1 ton per year."
Languages
Fluent Russian, Ukrainian and English.